Abstract The optimized synthesis of [5-oxo-4,4-diphenylimidazolidin-2-ylidene]cyanamide, which is known as 2-cyanoguanidinophenytoin (CNG-DPH) (3), and (imidazo[4,5-d]imidazole-2,5-diylidine)dicyanamide (4) has been reported in the present work.Furthermore, new Mannich bases derived from CNG-DPH were synthesized via its reaction with formaldehyde a
Background: Periprosthetic joint infection (PJI) represents a devastating consequence of total joint arthroplasty (TJA) because of its high morbidity and its sassy spheres candy high impact on patient quality of life.The lack of standardized preventive and treatment strategies is a major challenge for arthroplasty surgeons.The purpose of this artic
Abstract Background Arachnids possess highly specialized and unorthodox sense organs, such as the unique pectines of Scorpiones and the malleoli of Solifugae.While the external morphology, numbers, and shapes of sensory organs are widely used in taxonomic studies, little is known about the internal anatomy of these organs and their associated proce